B7-H4 is a positive regulator of antitumor immunity.

Oncoimmunology（2016）

引用 5|浏览2

暂无评分

摘要

B7-H4 (B7x, B7S1, VTCN1, DD-0110) is a member of the B7 superfamily that negatively regulates T cell responses. In addition, B7-H4 expression is increased on tumors and has been shown to be a negative prognostic marker for many cancers. Unexpectedly our recent study demonstrated that B7-H4 inhibited tumor growth and was required to promote effective antitumor responses..

查看译文

关键词

B7-H4,T lymphocytes,cancer,co-inhibitory molecules

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要