Six Degree-of-Freedom Image Guidance for Frameless Intracranial Stereotactic RadioSurgery with kilo-voltage Cone- Beam CT

Stereotactic radiosurgery (SRS) has been an effective treatment for the management of brain metastases and other brain diseases [1-6]. Traditionally, SRS is performed with the use of a stereotactic head ring frame. The head ring frame provides robust localization and minimal motion from CT-simulations to treatments [6-8]. However, the use of the conventional head ring often involves pain, general discomfort, and the need for surgical intervention. Recent developments in image-guidance and frameless immobilization enable target localization with increased accuracy, in order to deliver radiation more precisely to the tumor while sparing adjacent healthy tissue.