Hemodynamics effects of adrecizumab in sepsis rat

A Blet,M Sadoune, E Polidano, R Merval, C Bernard,JL Samuel,A Mebazaa

Intensive Care Medicine Experimental（2015）

引用 1|浏览24

暂无评分

摘要

Sepsis and septic shock still represent major health issues, with persisting high morbidity and mortality rates in critically ill patients. Cardiac dysfunction[1] occurs frequently during severe sepsis. Adrenomedullin (ADM) has been identified as a key mediator in vascular tone regulation[1]. A newly developed anti-ADM antibody Adrecizumab (ADZ) may improve hemodynamic dysfunction during resuscitated murine, cecal ligation and puncture (CLP)-induced septic shock[2].

查看译文

关键词

Septic Shock,Severe Sepsis,Mean Arterial Pressure,Hemodynamic Effect,Vascular Dysfunction

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要