130 Reproducibility of T1 and T2 Mapping in Health and Disease, and Assessment of T2 Variability Across the Normal Myocardium

Background T1 and T2 mapping detect myocardial fibrosis and oedema respectively. T1 values show segmental variation in mid ventricular SAX slice, making the identification of regional pathology difficult.We tested the reproducibility of T1 and T2 mapping in health and disease and regional variations of T2 values. Methods Patients with non-ischaemic cardiomyopathy (NICM, n-10), ischaemic heart disease (IHD, n-10) and 10 controls underwent T1 and T2 mapping in a single SAX slice on a 3T scanner using MOLLI and T2 multi-echo sequence. Two independent observers measured T1 and T2 values from quantitative maps in six standardised regions of interest. Intra- and inter-observer reproducibility of T1 and T2 mapping was assessed using Bland-Altman plots and Pearson’s correlation. Results Age was significantly higher in IHD group (p