Dynamic building energy performance analysis: A new adaptive control strategy for stringent thermohygrometric indoor air requirements

•A new optimal Model Reference Adaptive Control scheme for buildings is developed.•No a priori knowledge of building dynamics and parameters certainty is required.•Control robustness vs. disturbances and nonlinear unmodelled dynamics is proved.•Indoor air temperature/humidity conditions and comfort requirements are fulfilled.•Through DETECt PCM analyses and multi-simulations are performed without retuning.