Synthesis Of 2-Aminooxazolines And Spiro-2-Aminooxazolines By Using A Convenient Two-Step Inco-Mediated Reaction

Corey D. Anderson,Dean M. Wilson,Long Mao,Michele Ramirez-Weinhouse, Daniel D. Long, Christine M. Crane,Catherine Jolivet,Dewey Fanning,Valentina Molteni,Andreas Termin

SYNLETT（2013）

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摘要

A two-step reaction sequence yielding 2-aminooxazolines under mild conditions was developed. Both electron-rich and electron-deficient styrenes as well as functionalized primary and secondary amides could be used in the reaction to afford 2-aminooxazolines in reasonable yields.

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关键词

isocyanate,library generation,styrene,heterocycles,multicomponent reactions

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