Synthesis of Imidazolidine-2-(thi)ones via C2-Selective Oxidation and Thionation of 2-Imidazolinium Halides

Romano Orru,Eelco Ruijter,Marinus B Groen,Frans De Kanter, Hugo Van Oosterhout,Nanda E Sprenkels,Robin S Bon,M Mooijman

Synlett（2012）

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摘要

This article describes a scope study for the synthesis of imidazolidine-2-(thi)ones by selective oxidation or thionation of 2-imidazolinium halides, which in turn are synthesized by alkylation of 2-imidazolines obtained from an initial multicomponent reaction.

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关键词

alkylation,cyclization,heterocycles,imines,multicomponent reactions

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