Discovery of novel monosaccharides in animal glycans: natural occurrence of N-glycolylhexosamines (607.6)

Anne K Bergfeld,Roger Lawrence,Sandra Diaz,Oliver M T Pearce,Jeremy Van Vleet,Jeffrey D Esko,Biswa Choudhury,Ajit Varki

The FASEB Journal（2014）

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摘要

Metabolism of the major mammalian sialic acid N-glycolylneuraminic acid (Neu5Gc) generates N-glycolylglucosamine (GlcNGc) as a byproduct of its degradative pathway (1). Mammalian cells cultured wit...

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