The effect of a novel TRPA1 antagonist JNJ-41477670 on models of airway hyperactivity and inflammation in rats (660.6)

Anindya Bhattacharya,William A Eckert,Hong Ao,Alec D Lebsack,Jason C Rech,Alan D Wickenden

The FASEB Journal（2014）

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摘要

TRPA1 activation by respiratory irritants and pungent foods causes neurogenic inflammation, possibly contributing to wheezing, cough and dyspnea in humans. In this study we characterized JNJ-414776...

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