Quantitation of oxidative stress and base excision repair in skeletal muscle of high- and low-functioning elderly individuals

Anna-Maria Joseph,Silvia Tornaletti,Peter Adhihetty,Thomas Buford,Stephanie Wohlgemuth,Bhanuprasad Sandesara,Emanuele Marzetti,Christiaan Leeuwenburgh

The FASEB Journal（2014）

引用 2|浏览11

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摘要

Skeletal muscle aging is partly attributed to the oxidation of macromolecules caused by increased reactive oxygen species. DNA base excision repair (BER) pathways offer protection against oxidative...

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