The role of H2S bioavailability in endothelial dysfunction
Trends in Pharmacological Sciences(2015)
摘要
•Endothelial H2S bioavailability regulates endothelial proliferation and function.•H2S is an endothelium-derived hyperpolarizing factor.•Altered H2S bioavailability is a novel hallmark of endothelial dysfunction.•H2S bioavailability is a therapeutic target for remedying endothelial dysfunction.
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关键词
cystathionine gamma-lyase,endothelium-derived hyperpolarizing factor,gasotransmitters,heme oxygenase-1,hydrogen sulfide,nitric oxide
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