Personalized liposome–protein corona in the blood of breast, gastric and pancreatic cancer patients

•The liposome–protein corona varied among healthy subjects as well for identical diseases.•Zeta potential of the hard coronas from breast and gastric cancer were similar.•The liposome–protein corona of pancreatic cancer patients was less negative.•The corona from pancreatic cancer patients was more enriched than those of other cancers.•Nanoparticle-based technologies will be aimed at screening for early cancer detection.