Synergic effect of GSTP1 and blood manganese concentrations in Autism Spectrum Disorder

Mohammad H. Rahbar,Maureen Samms-Vaughan,Jianzhong Ma,Jan Bressler,Aisha S. Dickerson,Manouchehr Hessabi,Katherine A. Loveland,Megan L. Grove,Sydonnie Shakespeare-Pellington,Compton Beecher,Wayne McLaughlin,Eric Boerwinkle

Research in Autism Spectrum Disorders（2015）

引用 26|浏览22

暂无评分

摘要

•We studied the synergistic effect of blood manganese levels (Mn) and GSTP1 in ASD.•Odds of ASD was higher in children with Mn≥12μg/L and GSTP1 Ile/Ile genotype.•Children with Mn≥12μg/L and GSTP1 Ile/Ile genotype had 4 times higher odds of ASD.•Children with Mn≥12μg/L and Ile/Ile genotype had 6 times higher adjusted odds of ASD.

查看译文

关键词

Manganese,Autism Spectrum Disorder (ASD),Glutathione-S-transferase (GST) genes,Oxidative stress,Interactions,Jamaica

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要