Current understanding of chronic endometritis

Chronic endometritis (CE) is recognized as unusual plasmacyte infiltration within the endometrial stromal component. CE has been ignored in clinical practice, due to subtle symptoms, time-consuming diagnostic examinations, and benign pathology. The aetiology and pathogenesis of CE remain so far largely unknown. Recent studies, however, suggest the potential involvement of CE in reproductive failure and endometrial polyposis. In this review article, we aimed to outline the clinical and histopathologic features of CE and discuss the current problems and future prospects in its diagnosis, treatment, and management.