Abstract B4: Chromosome 17p13.1 (KCTD11), a smoking-related susceptible region linked to lung cancer risk in Korean populations

Lung cancer is the most common cause of cancer death worldwide. Smoking is known as the strongest single factor for the development of lung cancer. However, there are inherited genetic factors that cause different responses to cigarette smoking exposure among individuals. We tried to identify these differences in heavy smokers by examining copy number variations (CNVs) between lung cancer patients and healthy controls. Analysis by array comparative genomic hybridization (aCGH) showed 26 significant (P Citation Information: Clin Cancer Res 2010;16(14 Suppl):B4.