Mechanisms of action of bone morphogenetic proteins in cancer

Hayley Davis,Erna Raja,Kohei Miyazono,Yutaro Tsubakihara,Aristidis Moustakas

Cytokine & Growth Factor Reviews（2016）

引用 68|浏览23

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摘要

•Bone morphogenetic proteins act as tumour suppressors.•Bone morphogenetic proteins promote tumourigenesis.•Bone morphogenetic proteins regulate EMT and the tumour microenvironment.•Bone morphogenetic proteins promote osteolytic metastasis.

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关键词

BMP,Cancer,EMT,Metastasis,TGF-β

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