The overexpression of Thioredoxin-1 suppressing inflammation induced by methamphetamine in spleen

Xiaoli Wu, Xiang Li,Ye Li, Lingpin Kong, Jiaolong Fang,Xiaoshuang Zhou,Mei Li,Jinjing Jia,Jie Bai

Drug and Alcohol Dependence（2016）

引用 11|浏览1

暂无评分

摘要

•The methamphetamine (METH) induced dysfunction of immune system in spleen by increasing proinflammatory cytokines and decreasing anti-inflammatory cytokine.•METH regulated inflammatory cytokines through regulating their transcription factors. METH induced oxidative stress by decreasing Trx-1.•The overexpression of Trx-1 reversed these effects induced by METH.

查看译文

关键词

ASK1,CNS,DC,GATA3,HIV,HL-60,IFN-γ,IL-1β,IL-2,IL-4,IL-10,LPS,METH,NK,PAG,qRT-PCR,STAT4,STAT6,T-bet,TBP-2,Tg,Th,TNF-α,Trx-1,VDUP1,WT

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要