NECROTIZING ENTEROCOLITIS |[lpar]|NEC|[rpar]|, A RADIOGRAPHIC AND PATHOLOGIC MODEL

NEC in neonates is suspected by abdominal distension, feeding intolerance and Guaiac + stools but is first clinically confirmed by abnormal findings on radiographs of the abdomen. Using our previously described rabbit intestinal loop model for NEC, we prepared 30 cm loops in 12 weanling rabbits into which a suspension of 3% lactose, 1% purified bovine casein and a Gram negative bacteria capable of the mixed acid fermentation were injected. The blood supply was carefully preserved. Radiographs of the abdomen were taken 6 or 18 hrs. later. Following the radiographs the rabbits were opened to examine the intestines.