Induction of hormone-sensitive lipase/cholesteryl esterase gene expression by C/EBPα independently of the PKA pathway in the adrenocortical Y-1 cells

Steroids（2015）

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摘要

•C/EBPα induces LIPE expression encoding HSL one of the key enzymes of steroidogenesis.•C/EBPα effect on LIPE expression is independent of the stimulation of the PKA signaling pathway.•C/EBPα binds to a response element located in the −60bp fragment of LIPE promotor A.

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关键词

C/EBPα,LIPE induction,PKA,Y-1 cells

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