Synthesis, characterization and cytotoxic activity studies of two ruthenium(II) complexes

Wei Li,Bingjie Han,Ji Wang,Guangbin Jiang,Yangyin Xie,Ganjian Lin,Hongliang Huang,Yunjun Liu

Inorganica Chimica Acta（2014）

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摘要

Two Ru(II) complexes [Ru(phen)2(idpq)]2+ (1) and [Ru(dmp)2(idpq)]2+ (2) have been synthesized and characterized. Their cytotoxicity in vitro, apoptosis, ROS, mitochondrial membrane potential and cell cycle arrest were investigated.

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关键词

Ru(II) complexes,Cytotoxicity in vitro,Apoptosis,ROS,Mitochondrial membrane potential,Cell cycle arrest

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