MSPrecise: A molecular diagnostic test for multiple sclerosis using next generation sequencing

William H. Rounds,Edward A. Salinas, Tom B. Wilks,Mikhail K. Levin,Ann J. Ligocki,Carolina Ionete,Carlos A. Pardo,Steven Vernino,Benjamin M. Greenberg,Douglas W. Bigwood,Eric M. Eastman,Lindsay G. Cowell,Nancy L. Monson

Gene（2015）

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摘要

•The diagnostic MSPrecise supports identification of multiple sclerosis patients.•MSPrecise uses B cell antibody sequences from patient cerebrospinal fluid.•MSPrecise performs well in identifying MS among a broad cohort of neurological diseases.

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关键词

RRMS,OND,MS,CNS,SHM,CSF,VH4,NGS,HCN,JH,MF,RMF,CDR,AGS,IQR,OCB,DMT,CIS

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