Fluorescence Optical Tomography of Preclinical Glioma Models Using Spatial Frequency Domain Imaging

Fredric Leblond,Brian C Wilson,Soren D Konecky,Kolbein Kolste,Pablo A Valdes,Tyler B Rice,Bruce J Tromberg,Keith D Paulsen,David W Roberts,Christopher M Owen

IEEE Transactions on Biomedical Engineering（2012）

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摘要

Spatial frequency domain imaging of 5-aminolevulinic acid induced protoporphyrin IX was used to recover absorption, scattering, and fluorescence properties of glioblastoma multiforme in tissue-simulating phantoms and in vivo in a mouse model.

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