Intraoperative Monitoring of Photodynamic Therapy Efficacy using Diffuse Optical Spectroscopy in Mesotheloma Patients: Focusing on the Effect of PDT-induced Hypoxia

Steven M Albelda,Madeline E Winters, Julien Menko,Jarod Finlay, Timothy C Zhou,So Hyun Chung,Keith A Cengel, Charles B Simon,Joseph S Friedberg,Eli Glatstein,Arjun G Yodh,Theresa M Busch

IEEE Transactions on Biomedical Engineering（2014）

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摘要

We used Diffuse Optical Spectroscopy to measure the effect of PDT on hemoglobin concentration changes during intra-operative PDT for mesothelioma. Those with less PDT-created hypoxia had better prognosis than those with severe hypoxia.

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