The efficacy of fluticasone furoate administered in the morning or evening is comparable in patients with persistent asthma.

R D Kempsford,J Bal, A Baines, J Renaux, R Ravindranath,P S Thomas

Respiratory Medicine（2016）

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摘要

•Timing of once-daily fluticasone furoate (FF) was studied for efficacy in asthma.•Morning (AM) or evening (PM) FF100 μg, and placebo were compared.•Forced expiratory volume in 1 s (FEV1) was measured on Day 14.•AM and PM dosing were comparable for 24-h and pre-treatment FEV1.•There was also no difference in adverse event incidence between AM and PM dosing.

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关键词

Asthma,Inhaled corticosteroid,Fluticasone furoate,Efficacy,Morning dosing,Evening dosing

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