Alpha and Beta Type 1 Interferon Signaling: Passage for Diverse Biologic Outcomes

Cherie T. Ng,Juan L. Mendoza, K. Christopher Garcia,Michael B.A. Oldstone

Cell（2016）

引用 146|浏览18

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摘要

Type I interferon (IFN-I) elicits a complex cascade of events in response to microbial infection. Here, we review recent developments illuminating the large number of IFN-I species and describing their unique biologic functions.

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关键词

type 1 interferon,persistent viral infection,pathogenesis,interferon-beta,interferon-alpha,bacterial infection,interferon alpha-beta receptor

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