Determination of Sodium Tanshinone IIA Sulfonate in human plasma by LC-MS/MS and its application to a clinical pharmacokinetic study.

WeiWei Qin,Bin Wang,XiaoPei Lu,HaiMing Liu,Li Wang,WeiLin Qi

Journal of Pharmaceutical and Biomedical Analysis（2016）

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摘要

•An LC–MS/MS method for the quantification of STS in human plasma is proposed.•The pharmacokinetic profile of STS in human is reported.•Sample preparation should be under yellow light to ensure the stability of the STS.

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关键词

Sodium Tanshinone IIA Sulfonate,LC–MS/MS,Human plasma,Pharmacokinetic

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