Investigation of a Role for Ghrelin Signaling in Binge-Like Feeding in Mice Under Limited Access to High-Fat Diet.

•Mice given limited and intermittent access to a high-fat diet exhibit binge-like behavior.•GHSR knock-out mice consume less fat when access becomes less predictable.•GHSR knock-out mice show reduced c-Fos in the nucleus accumbens following high-fat diet.