Assessment of local blood flow with laser Doppler flowmetry in irradiated mandibular and frontal bone, an experiment in Göttingen minipigs.

Lucas J Poort, Monique M F Bloebaum,Roland A Böckmann,Ruud Houben, Marlies E P G Granzier,Frank J Hoebers,Peter A W H Kessler

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery（2015）

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摘要

We found a non-significant decrease in LDF values with an increase in radiation dose in the mandible and non-significant changes in the os frontale at 3 and 6 months. We consider this to represent the process of on-going fibrosis affecting the local blood flow in the mandible.

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