HIV-associated immune complex kidney disease

Key Points HIV infection is associated with numerous adverse renal manifestations, including HIV-associated nephropathy (HIVAN), HIV-associated immune complex kidney disease (HIVICD), and other glomerulonephritides Renal biopsy in patients infected with HIV is essential to differentiate HIVICD from other forms of HIV-associated kidney diseases, such as HIVAN or nephrotoxicity The development of HIVICD is the result of the complex interplay between host–pathogen interactions, genetic susceptibility, and environmental factors Data regarding the optimal treatment strategy for patients with HIVICD are limited