Genome-wide association analysis identifies TXNRD2 , ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma

Jessica N Cooke Bailey,Stephanie J Loomis,Jae H Kang,R Rand Allingham,Puya Gharahkhani,Chiea Chuen Khor,Kathryn P Burdon,Hugues Aschard,Daniel I Chasman,Robert P Igo Jr,Pirro G Hysi,Craig A Glastonbury,Allison Ashley-Koch,Murray Brilliant,Andrew A Brown,Donald L Budenz,Alfonso Buil,Ching-Yu Cheng,Hyon Choi,William G Christen,Gary Curhan,Immaculata De Vivo,John H Fingert,Paul J Foster,Charles Fuchs,Douglas Gaasterland,Terry Gaasterland,Alex W Hewitt,Frank Hu,David J Hunter,Anthony P Khawaja,Richard K Lee,Zheng Li,Paul R Lichter,David A Mackey,Peter McGuffin,Paul Mitchell,Sayoko E Moroi,Shamira A Perera,Keating W Pepper,Qibin Qi,Tony Realini,Julia E Richards,Paul M Ridker,Eric Rimm,Robert Ritch,Marylyn Ritchie,Joel S Schuman,William K Scott,Kuldev Singh,Arthur J Sit,Yeunjoo E Song,Rulla M Tamimi,Fotis Topouzis,Ananth C Viswanathan,Shefali Setia Verma,Douglas Vollrath,Jie Jin Wang,Nicole Weisschuh,Bernd Wissinger,Gadi Wollstein,Tien Y Wong,Brian L Yaspan,Donald J Zack,Kang Zhang, EPIC-Norfolk Eye Study,Robert N Weinreb,Margaret A Pericak-Vance,Kerrin Small,Christopher J Hammond,Tin Aung,Yutao Liu,Eranga N Vithana,Stuart MacGregor,Jamie E Craig,Peter Kraft,Gareth Howell,Michael A Hauser,Louis R Pasquale,Jonathan L Haines,Janey L Wiggs

NATURE GENETICS（2016）

引用 194|浏览101

暂无评分

摘要

Janey Wiggs, Jonathan Haines and colleagues identify three new susceptibility loci for primary open-angle glaucoma. The association signals map near genes implicated in ocular development ( FOXC1 ), neurodegeneration ( ATXN2 ) and mitochondrial function ( TXNRD2 ).

查看译文

关键词

glaucoma,foxc1,association,genome-wide,open-angle

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要