Current drug therapy and pharmaceutical challenges for Chagas disease
Acta Tropica(2016)
摘要
•Chagas disease is one of the greatest therapeutic challenges in tropical medicine.•Different strategies are being sought to overcome Benznidazole’s toxicity.•Parasitic persistence is the main cause of progression towards cardiomyopathy.•New drug candidates may struggle to reach the market in the future.
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关键词
Chagas disease,Trypanosoma cruzi,Trypanocidal treatment,Benznidazol,Nifurtimox,New medication
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