Grey Matter Atrophy Associated With Mild Cognitive Impairment in Parkinson's Disease.

Fu-Xiang Chen,De-Zhi Kang,Fu-Yong Chen,Ying Liu,Gang Wu,Xun Li,Liang-Hong Yu,Yuan-Xiang Lin,Zhang-Ya Lin

Neuroscience Letters（2016）

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摘要

•There exists extensive gray matter loss in patients with Parkinson’s disease (PD).•Early cognitive deficits in PD is related to gray matter atrophy.•Imaging biomarker for PD with mild cognitive impairment is proposed.

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关键词

PD,HC,PDNC,PD-MCI,VBM,PDD,MDS,MRI,ROI,GM,MoCA,MMSE,UPDRS III,H-Y Stage,MPRAGE,MNI,FWHM,ANOVA,AD

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