Discovery of EBI-907: A Highly Potent and Orally Active B-Raf(V600E) Inhibitor for the Treatment of Melanoma and Associated Cancers.
Bioorganic & Medicinal Chemistry Letters（2015）
Key words
B-RafV600E,Kinase,Pyrazolo[3,4-c]isoquinoline,Scaffold hopping,Cancer
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