Electrostatic Repulsion during Ferritin Assembly and its Screening by Ions

    Satsuki Takebe
    Satsuki Takebe
    Atsushi Kurobe
    Atsushi Kurobe

    Biochemistry, 2015.

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    Abstract:

    Escherichia coli non-heme-binding ferritin A (EcFtnA) is a spherical cage-like protein that is composed of 24 identical subunits. EcFtnA dissociates into 2-mers under acidic conditions and can reassemble into the native structure when the pH is increased. To understand how electrostatic interactions influence the assembly reaction, the de...More

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