Reduced GABA neuron density in auditory cerebral cortex of subjects with major depressive disorder.
Journal of Chemical Neuroanatomy(2016)
摘要
•Auditory cortex was evaluated in major depression and schizophrenia.•Lower GABA neuron density was found in major depression subjects.•Lower density was significant in calbindin and calretinin interneuron subtypes.•Comparable changes were not found in total neuron or glia cell populations.•The findings indicate wide-spread cortical GABA changes in major depression.
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关键词
Interneuron,Stereology,Sensory cortex,Human postmortem,Psychiatric,Schizophrenia,Major depression,Suicide
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