Abnormal wiring of the connectome in adults with high-functioning autism spectrum disorder

Ulrika Roine,Timo Roine,Juha Salmi,Taina Nieminen-von Wendt,Pekka Tani,Sami Leppämäki, Pertti Rintahaka,Karen Caeyenberghs,Alexander Leemans,Mikko Sams

Molecular Autism（2015）

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摘要

Recent brain imaging findings suggest that there are widely distributed abnormalities affecting the brain connectivity in individuals with autism spectrum disorder (ASD). Using graph theoretical analysis, it is possible to investigate both global and local properties of brain’s wiring diagram, i.e., the connectome.

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关键词

Autism spectrum disorder,Diffusion magnetic resonance imaging,White matter tract,Tractography,Connectivity,Connectome,Brain networks,Graph theoretical analysis

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