Lactobacillus rhamnosus GG supernatant promotes intestinal barrier function, balances Treg and TH17 cells and ameliorates hepatic injury in a mouse model of chronic-binge alcohol feeding.
Toxicology Letters（2016）
摘要
•LGG supernatant ameliorates experimental ALD in a chronic-binge alcohol exposure model.•LGG supernatant normalizes the balance of Treg and TH17 in peripheral blood of mice exposed to chronic-binge alcohol.•LGG supernatant decreases the serum level of IL-17 in chronic-binge alcohol mice model.
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关键词
Lactobacillus rhamnosus GG supernatant,T regulatory cells,T helper 17 cells,Alcohol,Hepatic injury,Intestinal permeability
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