Human umbilical vein endothelial cells promote the inhibitory activation of CD4(+)CD25(+)Foxp3(+) regulatory T cells via PD-L1.
Atherosclerosis（2016）
摘要
•HUVEC promote inhibitory activation of Tregs via PD-L1.•The interaction of HUVEC and Tregs require cell contact.•PD-L1 expressed on ECs may serve therapeutic role in atherosclerosis.
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关键词
Programmed death ligand-1,Regulatory T cells,Endothelial cells,Atherosclerosis
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