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Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models?

Journal of Molecular and Cellular Cardiology, (2016): 49-62

Cited: 45|Views9
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Abstract

Cardiac electrophysiology models have been developed for over 50years, and now include detailed descriptions of individual ion currents and sub-cellular calcium handling. It is commonly accepted that there are many uncertainties in these systems, with quantities such as ion channel kinetics or expression levels being difficult to measure ...More

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