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Evolution of translation machinery in recoded bacteria enables multi-site incorporation of nonstandard amino acids

Miriam Amiram,Adrian D Haimovich,Chenguang Fan,Yane-Shih Wang,Hans-Rudolf Aerni,Ioanna Ntai,Daniel W Moonan,Natalie J Ma,Alexis J Rovner,Seok Hoon Hong,Neil L Kelleher,Andrew L Goodman,Michael C Jewett,Dieter Söll,Jesse Rinehart,Farren J Isaacs

NATURE BIOTECHNOLOGY（2015）

引用 215|浏览27
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摘要
Non-standard amino acids are incorporated into proteins at large numbers of sites using evolved translation components in recoded bacteria.
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关键词
Biomaterials,Molecular engineering,Life Sciences,general,Biotechnology,Biomedicine,Agriculture,Biomedical Engineering/Biotechnology,Bioinformatics
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