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Cladribine added to daunorubicin-cytarabine induction prolongs survival of FLT3-ITD+ normal karyotype AML patients.

Marta Libura,Sebastian Giebel,Beata Piatkowska-Jakubas,Marta Pawelczyk,Izabella Florek,Karolina Matiakowska,Bozena Jazwiec,Katarzyna Borg,Iwona Solarska,Magdalena Zawada,Sylwia Czekalska,Jolanta Libura,Malgorzata Jakobczyk,Karolina Karabin,Monika Paluszewska,Malgorzata Calbecka,Justyna Gajkowska-Kulik,Grazyna Gadomska,Marek Kielbinski,Anna Ejduk,Dariusz Kata,Sebastian Grosicki,Agnieszka Wierzbowska,Slawomira Kyrcz-Krzemien,Krzysztof Warzocha,Kazimierz Kuliczkowski,Aleksander Skotnicki,Jerzy Holowiecki,Wieslaw Wiktor Jedrzejczak,Olga Haus

Blood（2015）

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摘要
To the editor:Internal tandem duplication in the FLT3 gene ( FLT3- ITD) has been recognized as a marker conferring poor outcome in patients with normal karyotype acute myeloid leukemia (NK-AML).[1][1] Because of the inferior outcome of FLT3- ITD+ NK-AML patients when treated with standard
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