Prenatal alcohol exposure inducing the apoptosis of mossy cells in hippocampus of SMS2-/- mice.

Lai Wang,Lin Wu,Xiaoqing Wang,Jiexin Deng,Zhanyou Ma,Wenjuan Fan,Weiya He,Jinbo Deng

Environmental Toxicology and Pharmacology（2015）

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摘要

•Mossy cells are sensitive to alcohol-induced neuroapoptosis.•Alcohol exposure makes apoptotic mossy cells in SMS2−/− mice increases.•Ceramide pathway is involved in the alcohol-induced neuroapoptosis.

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关键词

Ceramide,Prenatal alcohol exposure,Cell apoptosis,Sphingomyelin synthase 2 knockout mice,Mossy cell

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