Concomitant nodal involvement by Langerhans cell histiocytosis and Hodgkin's lymphoma.

A 10-year-old girl with a family history of Hodgkin's lymphoma presented with a 2month history of cervical lymphadenopathy and weight loss. Biopsy indicated concomitant nodal involvement by Langerhans cell histiocytosis and Hodgkin's lymphoma. Such an association is rare, especially so in children, but is not an isolated phenomenon, thereby prompting the question of whether Langerhans cell histiocytosis is a reactive or a neoplastic process.