Variations in the fate and biological effects of sulfamethoxazole, norfloxacin and doxycycline in different vegetable-soil systems following manure application.

•DOX dissipated faster in soils than SMZ and NOR.•DOX showed undetectable bioaccumulation and no negative effect on culture systems.•Radish accumulated higher SMZ and NOR than pakchoi.•Vegetable cultivation can limit or accelerate the dissipation of VAs.•Antibiotic effects on plant and soil microbial community related to plant species.