Neuromuscular Blocking Agent Cisatracurium Attenuates Lung Injury by Inhibition of Nicotinic Acetylcholine Receptor-α1

    Anesthesiology, 2015.

    Cited by: 12|Bibtex|Views2|Links
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    Keywords:
    attenuationinterleukin 6

    Abstract:

    Neuromuscular blocking agents (NMBAs) bind the nicotinic acetylcholine receptor α1 (nAChRα1) that also contributes to inflammatory signaling. Thus, the author hypothesized that the use of NMBA mitigates lung injury by improving ventilator synchrony and decreasing inflammatory responses.Lung injury was induced by intratracheal instillation...More

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