MARCH8 inhibits HIV-1 infection by reducing virion incorporation of envelope glycoproteins

Takuya Tada,Yanzhao Zhang,Takayoshi Koyama,Minoru Tobiume,Yasuko Tsunetsugu-Yokota,Shoji Yamaoka,Hideaki Fujita,Kenzo Tokunaga

NATURE MEDICINE（2015）

引用 95|浏览17

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摘要

Kenzo Tokunaga and colleagues report that MARCH8 inhibits the incorporation of the HIV-1 envelope glycoprotein into virus particles, thereby reducing viral infectivity.

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关键词

Retrovirus,Virus–host interactions,Biomedicine,general,Cancer Research,Metabolic Diseases,Infectious Diseases,Molecular Medicine,Neurosciences

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