The Syk tyrosine kinase suppresses malignant growth of human breast cancer cells

Nature, Volume 406, Issue 6797, 2000, Pages 742-747.

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Abstract:

Syk is a protein tyrosine kinase that is widely expressed in haematopoietic cells. It is involved in coupling activated immunoreceptors to downstream signalling events that mediate diverse cellular responses including proliferation, differentiation and phagocytosis1, 2, 3, 4. Syk expression has been reported in cell lines of epithelial or...More

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