Efficient set tests for the genetic analysis of correlated traits

Francesco Paolo Casale,Barbara Rakitsch,Christoph Lippert,Oliver Stegle

Nature methods（2015）

引用 79|浏览8

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摘要

The multi-trait set test (mtSet) is an efficient mixed-model method that enables genome-wide association tests for large cohorts and multiple quantitative traits using sets of variants to improve power and sensitivity, while addressing confounding due to population structure.

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关键词

Quantitative trait, Statistical methods

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