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Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting

Huanhuan Joyce Chen,Jian Sun,Zhiliang Huang, Harry Hou Jr, Myra Arcilla,Nikolai Rakhilin,Daniel J Joe,Jiahn Choi, Poornima Gadamsetty,Jeff Milsom,Govind Nandakumar,Randy Longman,Xi Kathy Zhou,Robert Edwards,Jonlin Chen,Kai Yuan Chen,Pengcheng Bu,Lihua Wang,Yitian Xu, Robert Munroe, Christian Abratte,Andrew D Miller,Zeynep H Gümüş,Michael Shuler,Nozomi Nishimura,Winfried Edelmann,Xiling Shen,Steven M Lipkin

Nature biotechnology（2015）

引用 30|浏览33
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摘要
New xenograft models of colorectal cancer exhibit metastasis to the liver, use immunocompetent mice and show improved resistance to chemotherapy.
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关键词
Cancer models,Life Sciences,general,Biotechnology,Biomedicine,Agriculture,Biomedical Engineering/Biotechnology,Bioinformatics
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