CuSO4/KI As Catalyst for the Synthesis of 1,4-Disubstituted-1,2,3-Triazolo-Nucleosides.

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS（2015）

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摘要

A simple and inexpensive procedure has been developed for the selective formation of 1,4-disubstituted-1,2,3-triazolo-nucleosides starting from organic azides and terminal alkynes, mediated by in situ generated copper(I) catalyst from readily available CuSO4 and KI.

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关键词

one-pot [3+2] cycloaddition,1,2,3-triazolyl nucleoside,click reaction,Copper catalysts,CuSO4/KI

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